KosherSwitch
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@blakeyrat said:
Did he tell you to make a video game where the hero holds two katanas and each katana has a rocket in the handle so he can fly like a superhero? Is... is your handle CrazyJim1? It totally is you, isn't it?
REVELATIONS!
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@dhromed said:
Down syndrome is not caused by the mutation of a gene, but by a gamete with an extra chromosome.
Yeah, I kind of just blurted out a reaction when I heard OldCrow say that genes don't mutate. which I believe goes against common knowledge.Mind you, Genetics and its related subjects are not my area of expertise and as such I'm going to refrain from posting any further preconceived ideas I hold to be true.
By the way, no one ask me but I consider myself an agnostic*
By this I mean I believe there may zero, one or more gods, but I don't really find that affects me much in my daily life. I'm
sureconfident a superior being would be too different from humans to be relatable to in any case. It's hard enough understanding fellow humans, already. For example: what do they mean with "god"? It's never the same exact thing.*If you go and read that, I mean a "weak" one in particular. See also possibilianism and apatheism.
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@dhromed said:
@boomzilla said:
the role of proper brace positioning in good coding standards.
I successfully adjusted to a life of same-line.
Gah! OK, new topic: ad blockers are awesome!
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@dhromed said:
I've tried putting all my code in the same line too, but it gets impractical after a while.@boomzilla said:
the role of proper brace positioning in good coding standards.
I successfully adjusted to a life of same-line.
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@dhromed said:
@blakeyrat said:
Did he tell you to make a video game where the hero holds two katanas and each katana has a rocket in the handle so he can fly like a superhero? Is... is your handle CrazyJim1? It totally is you, isn't it?
REVELATIONS!
I don't have a memory trace of ever making a videogame. I usually work with 8-bit embedded systems, so it would be unlikely anyway. Does this game have a name?
@eViLegion said:
Aw shit... I declined to do that.
</p><p> </blockquote></p><p>Can you actually decline to do that? I thought that it was mandatory. Depending on the country, it has even been mandatory to some domesticated feline, despite poor undertanding of English. </p><p> </p>
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@Zecc said:
@dhromed said:
I've tried putting all my code in the same line too, but it gets impractical after a while.@boomzilla said:
the role of proper brace positioning in good coding standards.
I successfully adjusted to a life of same-line.
For js, you can always just run Closure before every check-in.
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@boomzilla said:
the role of proper brace positioning in good coding standards.
I don't give two shits what you use, because I can always just dump it into VS and Ctrl+E, Ctrl+D it into my preferred style.
@mikeTheLiar said:
Also, that didn't work.It's not the thread, it's the 700 email notifications......
....... ...... what's this?.........
.....options?
Oh goddam it.
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@Zecc said:
Mind you, Genetics and its related subjects are not my area of expertise and as such I'm going to refrain from posting any further preconceived ideas I hold to be true.
It's not my job exactly either. I agree, no more genetics.
@Zecc said:
For example: what do they mean with "god"? It's never the same exact thing.
Well, I can tell you my version. When I say God, I mean the Lord, as depicted in the Bible. Just in case anyone was wondering. He's the only living god, as far as I know. I wouldn't worship any of the dead ones; that would be crazy.
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I tend to follow the brace practises already present in the code base, if there is a consistent one. ...And if it doesn't involve 500+ character lines. Some proprietary IDEs barf on too long lines.
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@OldCrow said:
Can you actually decline to do that? I thought that it was mandatory. Depending on the country, it has even been mandatory to some domesticated feline, despite poor undertanding of English.
It is basically mandatory in the UK, but you can defer it for various reasons, like having already booked a holiday. Essentially, you can get out of it if you're not just trying to duck out but have a genuinely good reason. You may not defer twice though.
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@eViLegion said:
@OldCrow said:
Can you actually decline to do that? I thought that it was mandatory. Depending on the country, it has even been mandatory to some domesticated feline, despite poor undertanding of English.
It is basically mandatory in the UK, but you can defer it for various reasons, like having already booked a holiday. Essentially, you can get out of it if you're not just trying to duck out but have a genuinely good reason. You may not defer twice though.
I would have thought that not understanding spoken English is a good enough reason to defer indefinitely. But if not, then I start to see how this happened:
Sal the Cat summoned for jury service... and court rules he 'must attend'
Anna Esposito thought the Boston court service had made a mistake when she was told her tabby Sal would have to attend court.
Then again, this article says it was in Boston, not UK. It wasn't a second deferment either though.
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What an astonishing article!
You'd have thought the jury comissioner would have said
"Hah... thats an amusing mistake! Yes, obviously he doesn't have to do jury duty."
Jobsworths.
I think I wouldn't have responded to the initial summons, just to see what they do about it. Getting something like this escalated would be awesome!
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@OldCrow said:
You're mistaken. DNA analysis of cancer cells often shows the defects in genes, not present in the host. Very often a tumor even have cell lines with different mutations. And the tumor can undergo pretty quick evolution, developing resistance to a particular chemotherapy agent, so it stops working.@Zecc said:
@OldCrow said:
Also, there is no such thing as "random mutation" when a new individual's DNA is born. There is randomness involved, yes; which genes the child gets from the sum of its parents is random. But no actual mutation or creation of totally new sequences happens. The "genes" or "sequence strings" don't break; they're either taken or left out.
Good news for people with cancer!And Down Syndrome.
Sorry for being so vocal, but this is too good to pass up.
I said that there were no mutations "when a new individual's DNA is born", so it kind of rules out cancer. Cancer's a good example against evolution in that it doesn't actually go into the gene pool, unless it happens to your sperm.
Which brings us nicely to the Down Syndrome. Yes, you're right it seems to involve gene mutations. But what I'd really like to know it the ratio of beneficial and catastrophic(i.e. Down) mutations. Considering the length of the full DNA sequence, the odds are pretty bad. But the most severely damaged ones simply don't get to the fetus stage.
Edit:
Typos
Also, what I'm trying to say is: The mutations are so rarely beneficial and so often Down that a million years with a population of a billion people would still not enrich the pool much. But you did have a good counter-argument. Well played, sir.
Mutations are often benign, as in very slightly beneficial or detrimental. Whether a particular mutation will propagate to most of the population or not, depends on many factors. But accumulation of mutations creates genetic diversity, and one day next mutation (together with previous benign changes) can create a new function which may be VERY beneficial or VERY detrimental.
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@OldCrow said:
You haven't heard of BRCA genes, have you?@Buttembly Coder said:
@OldCrow said:
Cancer's a good example against evolution in that it doesn't actually go into the gene pool, unless it happens to your sperm.
I forgot about that part where cancer always kills people before they have kids. Cancer can and does persist through family lines.Oh, they often have kids, since they want to leave a mark in this world before they go. A heritage, if you will.
But the kids tend to not inherit the cancer, which causes the mutation to be lost. Cancer is inherited in three generations approximately... never. But I'm sure you'll find some individual family that has this; the world is still wast.
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@OldCrow said:
There is no single "cancer" disease. Cancer can be defined as unconstrained growth (or propagation of certain cell type) which disturbs the viability of the host, by consuming its nutrients and breaking vital functions (such as hematopoetics).@Buttembly Coder said:
@OldCrow said:
Oh, they often have kids, ...But the kids tend to not inherit the cancer, which causes the mutation to be lost. Cancer is inherited in three generations approximately... never.
Congratulations, you're close to figuring out how punnett squares work. each copy of a gene has basically a one in two chance to be passed on (greatly simplifying things, as you are a great simpleton), over three generations, that's one in eight, or "approximately never", if you use Christian Math, apparently.Actually, "cancer" is defined as growth that does not share an individual's DNA. Being prone to getting one can be hereditary. But the actual cancer is not carried in your DNA.
Therefore, the only way to really inherit cancer is to get infected from the mother while in womb.
Which one of us does not understand genes again?
Some cancers are caused by random mutations in a single cell, which turns off the self-limiting switches (allows the cell to divide without constraints). Some cancers are caused by a defect already inherited, but the gene not turned on initially. Some cancers (such as cervical) are caused by virus RNA embedding itself in the cells.
Mutations happen all the time in your own cells. The mutations that happen in your germ cells will be passed to your offspring (if it's viable), but typically won't affect you. The mutations in your body may not affect functions, or may cause cancer. That's the matter of luck.
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@MiffTheFox said:
@bridget99 said:
I'm not sure I agree with categorical statements like that. But it is weird how so many people are willing to be against things because of the ambiguous pronouncements of a powerful alien who may or may not have walked the Earth 2,000 years ago, while so few people are willing to say things like "I'm against abortion because I like babies." I think I would sympathize more with the latter sort of argument than with the former, space alien-based one.
Except nobody's oging to come out and say "I'm against homosexuals getting married because I believe marriage is about a man dominating women" or "I'm adamant you join my religion because that's how it propagates".
I might not use the exact same verbiage, but I think that first statement could be reformulated into something far more rational than what the hetero marriage kooks actually say.
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@Zecc said:
By this I mean I believe there may zero, one or more gods, but I don't really find that affects me much in my daily life. I'm
sureconfident a superior being would be too different from humans to be relatable to in any case. It's hard enough understanding fellow humans, already. For example: what do they mean with "god"? It's never the same exact thing.A good friend of mine compared his beliefs to the Daedric Princes from The Elder Scrolls, in that he believes that any potential deities wouldn't give two shits about humanity unless it was to their own benefit.
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@MiffTheFox said:
@Zecc said:
By this I mean I believe there may zero, one or more gods, but I don't really find that affects me much in my daily life. I'm
sureconfident a superior being would be too different from humans to be relatable to in any case. It's hard enough understanding fellow humans, already. For example: what do they mean with "god"? It's never the same exact thing.A good friend of mine compared his beliefs to the Daedric Princes from The Elder Scrolls, in that he believes that any potential deities wouldn't give two shits about humanity unless it was to their own benefit.
What if they're just really really bored?
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@Ben L. said:
@MiffTheFox said:@Zecc said:
What if they're just really really bored?By this I mean I believe there may zero, one or more gods, but I don't really find that affects me much in my daily life. I'm
sureconfident a superior being would be too different from humans to be relatable to in any case. It's hard enough understanding fellow humans, already. For example: what do they mean with "god"? It's never the same exact thing.A good friend of mine compared his beliefs to the Daedric Princes from The Elder Scrolls, in that he believes that any potential deities wouldn't give two shits about humanity unless it was to their own benefit.
Entertainment is a benefit.
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@OldCrow said:
Well, I can tell you my version. When I say God, I mean the Lord, as depicted in the Bible. Just in case anyone was wondering. He's the only living god, as far as I know. I wouldn't worship any of the dead ones; that would be crazy.
That... doesn't help at all. I don't know how you interpret the Bible.Heck, I don't even know what you're referring to when you say "the Bible".
In any case, if your interpretation is literal then I think you're confusing the metaphor for its intent.
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Please shut up about me.
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@OldCrow said:
[...] my primary proof is "God told me so". And He has verified His persona to me directly. To hear His testimony, you'll have to listen to Him yourself; I couldn't do that for you, unfortunately.
Thank you for making my fight for decriminalizing LSD, peyote, and psylocibin mushrooms that much harder, asshole. No one's gonna let me have the good stuff when you're "talking to God."
